Prime Minister Justin Trudeau and US President Donald Trump are due to meet on Tuesday during a NATO summit in London.
Trudeau and Trump are among the 29 NATO leaders in the UK to commemorate the alliance's 70th anniversary.
The meeting will take place at Winfield House, the British residence of the US ambassador.
Trump had previously accused other NATO countries of not spending enough on defense and considered reducing US involvement.
As Canada faces pressure from the alliance to spend more on its armed forces, Trudeau is expected to highlight the country's strong support for Ukraine. There are currently about 200 Canadian military personnel helping to train the Ukrainian military.
The last time Trump and Trudeau met was at the G7 summit in France in August for a discussion on trade and diplomacy.
They made brief remarks during a photo shoot about their shared commitment to see the new US trade agreement enacted.
The renegotiated NAFTA agreement could very well be a point of discussion for both leaders as they meet at the NATO summit.
In an effort to ratify the deal, Deputy Prime Minister Chrystia Freeland traveled to Washington, DC last week to meet with US and Mexican trade officials.